rs1268789
This variant is located in the FRAS1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
strand of hair shape
Liu F et al. “Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair.” Human Molecular Genetics 27(3):559-575 (2018)
Allele T
OR 0.04
p 1.0e-12
N 16,763
Meta-analysisLarge GWAS
multi-ancestry
About FRAS1
This gene encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development. Mutations in this gene cause Fraser syndrome, a multisystem malformation that can include craniofacial, urogenital and respiratory system abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
View all FRAS1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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