rs12692737
This is a regulatory region variant variant in the COBLL1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
smoking behavior, BMI-adjusted waist-hip ratio
Justice AE et al. “Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.” Nature Communications 8:14977 (2017)
Allele A
OR 0.03
p 5.0e-8
N 191,661
Meta-analysisLarge GWAS
multi-ancestry
BMI-adjusted waist-hip ratio
Shungin D et al. “New genetic loci link adipose and insulin biology to body fat distribution.” Nature 518(7538):187-196 (2015)
Allele A
OR 0.03
p 4.0e-10
N 143,480
Large GWAS
multi-ancestry
About COBLL1
Enables cadherin binding activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
View all COBLL1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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