rs12714592

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

social inhibition quality, attention deficit hyperactivity disorder, substance abuse

Karlsson Linnér R et al. “Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.” Nature Neuroscience 24(10):1367-1376 (2021)

Allele A

OR 0.01

p 2.0e-21

N 2,776,348

Large GWAS

European

age at first sexual intercourse measurement

Mills MC et al. “Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.” Nature Human Behaviour 5(12):1717-1730 (2021)

Allele A

OR 0.02

p 1.0e-20

N 397,338

Large GWAS

European

Day FR et al. “Physical and neurobehavioral determinants of reproductive onset and success.” Nature Genetics 48(6):617-623 (2016)

Allele A

OR 0.03

p 2.0e-10

N 125,667

Large GWAS

European

smoking status measurement

Cai N et al. “Minimal phenotyping yields genome-wide association signals of low specificity for major depression.” Nature Genetics 52(4):437-447 (2020)

Allele C

OR 1.04

p 5.0e-11

N 336,066

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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