rs12727848

This is a downstream gene variant variant in the GCSAML gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gut microbiome measurement, allergen exposure measurement

Stickley SA et al. “Gene-by-environment interactions modulate the infant gut microbiota in asthma and atopy.” The Journal of Allergy and Clinical Immunology 156(2):433-448 (2025)

Allele G

OR —

β 0.020

p 5.0e-8

N 688

Small GWAS

multi-ancestry

About GCSAML

This gene encodes a protein thought to be a signaling molecule associated with germinal centers, the sites of proliferation and differentiation of mature B lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

View all GCSAML variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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