rs12906348

This is a intron variant variant in the ZNF592 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

heart failure

Lee DSM et al. “Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum.” Nature Genetics 57(4):829-838 (2025)

Allele A

OR 0.03

p 6.0e-12

N 2,358,556

Large GWAS

multi-ancestry

About ZNF592

This gene is thought to play a role in a complex developmental pathway and the regulation of genes involved in cerebellar development. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia. [provided by RefSeq, Jan 2011]

View all ZNF592 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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