rs12928520
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
white matter hyperintensity measurement
Persyn E et al. “Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants.” Nature Communications 11(1):2175 (2020)
Allele T
OR 7.31
p 1.0e-13
N 45,204
Large GWAS
multi-ancestry
Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele T
OR 0.07
p 2.0e-12
N 21,381
Major Consortium StudyLarge GWAS
European
Armstrong NJ et al. “Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.” Stroke 51(7):2111-2121 (2020)
Allele T
OR 0.04
p 4.0e-11
N 18,226
Large GWAS
multi-ancestry
neuroimaging measurement
Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele T
OR 0.07
p 9.0e-11
N 20,860
Major Consortium StudyLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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