rs13074711

This is a intergenic variant variant.

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GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

aspartate aminotransferase measurement

Chen VL et al. “Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.” Nature Communications 12(1):816 (2021)
Allele T
OR 9.27
p 2.0e-20
N 389,565
Large GWAS
multi-ancestry

sex hormone-binding globulin measurement

Harrison S et al. “Testosterone and socioeconomic position: Mendelian randomization in 306,248 men and women in UK Biobank.” Science Advances 7(31) (2021)
Allele C
OR 0.78
p 2.0e-10
N 148,248
Major Consortium StudyLarge GWAS
European

testosterone measurement

Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele T
OR 0.03
p 3.0e-9
N 194,453
Large GWAS
European
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Research that mentions this SNP (1)

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A genome-wide association study of breast cancer in women of African ancestry
AssociationN=21,921Chen F. et al.(2013)· Human Genetics

Genome-wide association study of breast cancer in 3,153 African American cases and 2,831 controls, with replication in 3,607 cases and 11,330 controls of African ancestry. Two novel susceptibility loci reached statistical significance: rs4322600 at 14q31 (OR=1.18, p=4.3×10⁻⁶) and rs10510333 at 3p26 (OR=1.15, p=1.5×10⁻⁵). These variants represent novel risk loci not previously identified in other populations.

Traits studied:Breast cancer
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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