rs13186787
This is a coding sequence variant variant in the GALNT10 gene.
▶Research that mentions this SNP (1)
▶The association of common polymorphisms in miR-196a2 with waist to hip ratio and miR-1908 with serum lipid and glucoseAssociationN=73,014Mohsen Ghanbari et al.(2015)· Obesity
Two miRNA genetic variants were identified as significantly associated with cardiometabolic phenotypes: rs11614913 in miR-196a2 associated with waist-to-hip ratio (P=1.7e-25), and rs174561 in miR-1908 associated with lipid and glucose traits. Functional analyses revealed these variants affect pre-miRNA processing and regulate target genes involved in fat distribution and lipid metabolism.
About GALNT10
This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010]
View all GALNT10 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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