rs13236689

This is a intron variant variant in the CD36 gene.

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GWAS Catalog Trait Associations (7)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

nidogen-2 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.05
p 8.0e-24
N 47,745
Large GWAS
European

vascular endothelial growth factor A level

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.04
p 4.0e-20
N 47,745
Large GWAS
European

C-C motif chemokine 14 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.04
p 4.0e-14
N 47,745
Large GWAS
European

level of junctional adhesion molecule A in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.04
p 5.0e-13
N 47,745
Large GWAS
European

biglycan measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.04
p 2.0e-12
N 47,745
Large GWAS
European

platelet count

Qayyum R et al. “A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans.” Plos Genetics 8(3):e1002491 (2012)
Allele T
OR 4.18
p 3.0e-9
N 16,388
Meta-analysisLarge GWAS
African American or Afro-Caribbean
Hu Y et al. “Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study.” Bmc Genomics 22(1):432 (2021)
Allele T
OR 0.06
p 1.0e-8
N 16,201
Large GWAS
African American or Afro-Caribbean

About CD36

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

View all CD36 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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