rs13277355

▶

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

asthma

Han Y et al. “Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma.” Nature Communications 11(1):1776 (2020)

Allele A

OR —

p 3.0e-15

N 536,345

Large GWAS

multi-ancestry

Valette K et al. “Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank.” Communications Biology 4(1):700 (2021)

Allele A

OR 0.04

p 3.0e-8

N 408,422

Major Consortium StudyLarge GWAS

European

Zhu Z et al. “Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.” The European Respiratory Journal 54(6) (2019)

Allele A

OR 1.04

p 2.0e-8

N 394,283

Large GWAS

multi-ancestry

Ferreira MAR et al. “Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.” American Journal of Human Genetics 104(4):665-684 (2019)

Allele A

OR 1.05

p 2.0e-11

N 341,215

Large GWAS

European

asthma, Eczematoid dermatitis, allergic rhinitis

Johansson Å et al. “Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema.” Human Molecular Genetics 28(23):4022-4041 (2019)

Allele A

OR 1.04

p 6.0e-13

N 346,545

Major Consortium StudyLarge GWAS

European

childhood onset asthma

Pividori M et al. “Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.” The Lancet. Respiratory Medicine 7(6):509-522 (2019)

Allele A

OR 1.11

p 2.0e-10

N 327,670

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

rs13277355

GWAS Catalog Trait Associations (3)

asthma

asthma, Eczematoid dermatitis, allergic rhinitis

childhood onset asthma

Community Wiki

Comments