rs13287517

This is a upstream gene variant variant in the HAUS6 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

thyroid carcinoma

White SL et al. “Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.” Nature Genetics 58(2):307-316 (2026)

Allele C

OR 0.13

p 9.0e-26

N 2,106,366

Large GWAS

European

prostate carcinoma, type 2 diabetes mellitus

Ray D et al. “A powerful method for pleiotropic analysis under composite null hypothesis identifies novel shared loci between Type 2 Diabetes and Prostate Cancer.” Plos Genetics 16(12):e1009218 (2020)

Allele C

OR —

p 1.0e-14

N 801,624

Large GWAS

European

About HAUS6

The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. This protein may have a role in efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification. Pseudogenes of this gene are located on chromosomes 7 and 20. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]

rs13287517

GWAS Catalog Trait Associations (2)

thyroid carcinoma

prostate carcinoma, type 2 diabetes mellitus

About HAUS6

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