rs13335629

This is a intron variant variant in the FAM234A gene.

▶

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

mean corpuscular hemoglobin concentration

Chen Z et al. “Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.” Human Molecular Genetics 22(12):2529-38 (2013)

Allele A

OR 0.33

p 9.0e-48

N 16,485

Large GWAS

multi-ancestry

hemoglobin measurement

Kowalski MH et al. “Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.” Plos Genetics 15(12):e1008500 (2019)

Allele A

OR 0.21

p 1.0e-43

N 43,187

Major Consortium StudyLarge GWAS

multi-ancestry

Chen Z et al. “Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.” Human Molecular Genetics 22(12):2529-38 (2013)

Allele A

OR 0.19

p 3.0e-23

N 16,485

Large GWAS

multi-ancestry

erythrocyte count

Chen Z et al. “Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.” Human Molecular Genetics 22(12):2529-38 (2013)

Allele A

OR 0.17

p 7.0e-24

N 16,485

Large GWAS

multi-ancestry

Hodonsky CJ et al. “Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.” Plos Genetics 13(4):e1006760 (2017)

Allele A

OR 0.15

p 2.0e-13

N 12,502

Large GWAS

Hispanic or Latin American

erythrocyte volume

Chen Z et al. “Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.” Human Molecular Genetics 22(12):2529-38 (2013)

Allele A

OR 0.65

p 4.0e-22

N 16,485

Large GWAS

multi-ancestry

About FAM234A

Located in cell surface. [provided by Alliance of Genome Resources, Jul 2025]

View all FAM234A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…