rs13342232

This is a synonymous variant in the SLC16A11 gene — it does not change the protein's amino acid sequence.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

type 2 diabetes mellitus

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele G

OR 0.15

p 7.0e-19

N 177,415

Large GWAS

East Asian

Vujkovic M et al. “Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis.” Nature Genetics 52(7):680-691 (2020)

Allele G

OR 0.13

p 1.0e-15

N 216,287

Meta-analysisLarge GWAS

East Asian, South Asian

About SLC16A11

Enables pyruvate transmembrane transporter activity. Involved in lipid metabolic process. Located in endoplasmic reticulum membrane and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all SLC16A11 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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