rs1340910297
This variant is located in the TMEM116 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Alzheimer disease, family history of Alzheimer’s disease
Willett JDS et al. “Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses.” Alzheimer's & Dementia : the Journal of the Alzheimer's Association 21(2):e14592 (2025)
Allele A
OR —
p 1.0e-9
N 404,467
Large GWAS
multi-ancestry
About TMEM116
Predicted to be involved in signal transduction. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all TMEM116 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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