rs1345467
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
optic disc size trait
Springelkamp H et al. “Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.” Nature Communications 5:4883 (2014)
Allele G
OR 0.01
p 4.0e-13
N 21,094
Meta-analysisLarge GWAS
multi-ancestry
optic disc area
Bonnemaijer PWM et al. “Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.” Communications Biology 2:435 (2019)
Allele G
OR 0.03
p 3.0e-11
N 24,509
Large GWAS
European
Springelkamp H et al. “New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.” Human Molecular Genetics 26(2):438-453 (2017)
Allele G
OR 0.04
p 4.0e-13
N 22,504
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…