rs1352714
This variant is located in the DCHS2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Graves disease, thyrotoxic periodic paralysis
Zhao SX et al. “Assessment of Molecular Subtypes in Thyrotoxic Periodic Paralysis and Graves Disease Among Chinese Han Adults: A Population-Based Genome-Wide Association Study.” Jama Network Open 2(5):e193348 (2019)
Allele T
OR 1.58
p 1.0e-8
N 2,331
Large GWAS
East Asian
▶ClinVar annotation
About DCHS2
This gene encodes a large protein that contains many cadherin domains and likely functions in cell adhesion. Genome-wide association studies suggest that this gene may be important in Alzheimer's disease, compressive strength index, and appendicular lean mass. [provided by RefSeq, May 2017]
View all DCHS2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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