rs138429240
This is a protein-altering variant in the THAP3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of kynurenine--oxoglutarate transaminase 1 in blood serum
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.64
p 4.0e-53
N 47,745
Large GWAS
European
About THAP3
Predicted to enable DNA binding activity and zinc ion binding activity. Involved in positive regulation of transcription by RNA polymerase II. [provided by Alliance of Genome Resources, Jul 2025]
View all THAP3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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