rs138681708
This variant is located in the PAMR1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
amount of inactive serine protease PAMR1 (human) in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.23
p 7.0e-14
N 47,745
Large GWAS
European
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitterAbout PAMR1
Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
View all PAMR1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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