rs1388551

This is a intron variant variant in the ZNF385D gene.

Research that mentions this SNP (1)

Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women’s Health Initiative SHARe Study
AssociationN=11,687Digna R. Velez Edwards et al.(2013)· Human Genetics

A genome-wide gene-environment interaction study examined 8,203 African-American and 3,484 Hispanic postmenopausal women from the Women's Health Initiative SHARe GWAS for SNP interactions with lifestyle factors (smoking, diet, physical activity, alcohol) on BMI and waist-to-hip ratio. The strongest BMI gene-environment interaction across cohorts was rs10133840 with smoking (beta=-0.01, P=3.81×10^-7), and the strongest WHR interaction in African-Americans was rs9557704 (ITGBL1) with dietary energy intake (beta=-0.04, P=2.17×10^-7).

Traits studied:Body Mass Index (BMI)ObesityWaist-to-Hip Ratio (WHR)

About ZNF385D

Enables sequence-specific double-stranded DNA binding activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all ZNF385D variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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