rs139016727

This is a upstream gene variant variant in the ZNF511-PRAP1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of disintegrin and metalloproteinase domain-containing protein 8 in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele G

OR 0.63

p 3.0e-118

N 47,745

Large GWAS

European

About ZNF511-PRAP1

This locus represents naturally occurring readthrough transcription between the neighboring ZNF511 (zinc finger protein 511) and PRAP1 (proline-rich acidic protein 1) genes on chromosome 10. The putative readthrough transcript may encode a fusion protein that shares sequence identity with each individual gene product and may be involved in the regulation of gene promoters, particularly those found on transfected plasmids. [provided by RefSeq, Apr 2017]

View all ZNF511-PRAP1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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