rs139797380
This is a regulatory region variant variant in the SLC35D3 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
coffee consumption measurement, tea consumption measurement
Said MA et al. “Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus.” Journal of the American Heart Association 9(24):e016808 (2020)
Allele C
OR 0.11
p 4.0e-15
N 362,316
Large GWAS
European
diet measurement
Cole JB et al. “Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations.” Nature Communications 11(1):1467 (2020)
Allele C
OR 0.06
p 4.0e-11
N 449,210
Major Consortium StudyLarge GWAS
European
tea consumption measurement
Said MA et al. “Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus.” Journal of the American Heart Association 9(24):e016808 (2020)
Allele C
OR 0.08
p 9.0e-9
N 395,866
Large GWAS
European
About SLC35D3
Enables UDP-glucose transmembrane transporter activity. Involved in UDP-glucose transmembrane transport. Is active in synaptic vesicle membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all SLC35D3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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