rs140049238

This variant is located in the SMC2 gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

2 submitters

not specified; Nonpapillary renal cell carcinoma; Thymoma

About SMC2

Predicted to enable chromatin binding activity. Involved in mitotic chromosome condensation and positive regulation of chromosome condensation. Located in condensed chromosome; cytoplasm; and nuclear lumen. Part of condensin complex. Implicated in colon adenocarcinoma. Biomarker of colorectal cancer. [provided by Alliance of Genome Resources, Jul 2025]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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