rs140089781
This is a intron variant variant in the CTNNA2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
alcohol consumption quality
Clarke TK et al. “Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).” Molecular Psychiatry 22(10):1376-1384 (2017)
Allele A
OR 0.02
p 4.0e-8
N 112,117
Major Consortium StudyLarge GWAS
European
About CTNNA2
Enables actin filament binding activity. Involved in negative regulation of Arp2/3 complex-mediated actin nucleation; regulation of neuron migration; and regulation of neuron projection development. Located in cytoplasm. Implicated in complex cortical dysplasia with other brain malformations. [provided by Alliance of Genome Resources, Jul 2025]
View all CTNNA2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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