rs140527149
This variant is located in the AGMAT gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
4-guanidinobutanoate measurement
Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)
Allele C
OR 0.46
p 8.0e-236
N 8,144
Large GWAS
European
About AGMAT
Enables arginase activity; guanidinobutyrase activity; and guanidinopropionase activity. Predicted to be involved in putrescine biosynthetic process from arginine, via agmatine. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
View all AGMAT variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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