rs140608390
This is a intron variant variant in the CYP27C1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
protein C measurement
Pankow JS et al. “Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities).” Arteriosclerosis, Thrombosis, and Vascular Biology 37(3):589-597 (2017)
Allele C
OR 0.53
p 7.0e-24
N 13,484
CohortLarge GWAS
multi-ancestry
About CYP27C1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. [provided by RefSeq, Jul 2008]
View all CYP27C1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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