rs140641478
This is a downstream gene variant variant in the SPACA6 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of sialic acid-binding Ig-like lectin 5 in blood serum
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.29
p 1.0e-17
N 47,745
Large GWAS
European
About SPACA6
Enables protein-macromolecule adaptor activity. Involved in sperm-egg recognition. Is active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all SPACA6 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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