rs140680370

This is a regulatory region variant variant in the LMNB1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body fat percentage

Costa-Urrutia P et al. “Genome-Wide Association Study of Body Mass Index and Body Fat in Mexican-Mestizo Children.” Genes 10(11) (2019)

Allele A

OR 0.20

p 1.0e-8

N 828

Small GWAS

Hispanic or Latin American

About LMNB1

This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

View all LMNB1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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