rs1408272

This is a regulatory region variant variant in the LOC124901285 gene.

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GWAS Catalog Trait Associations (7)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

mean corpuscular hemoglobin

van der Harst P et al. “Seventy-five genetic loci influencing the human red blood cell.” Nature 492(7429):369-75 (2012)
Allele G
OR 0.03
p 5.0e-67
N 71,861
Large GWAS
multi-ancestry
Ganesh SK et al. “Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.” Nature Genetics 41(11):1191-8 (2009)
Allele G
OR 0.02
p 4.0e-39
N 24,167
Major Consortium StudyLarge GWAS
European
Ferreira MA et al. “Sequence variants in three loci influence monocyte counts and erythrocyte volume.” American Journal of Human Genetics 85(5):745-9 (2009)
Allele G
OR 0.32
p 1.0e-11
N 6,015
Large GWAS
European

fatty acid amount

Sun Y et al. “GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.” Hgg Advances 6(4):100470 (2025)
Allele G
OR —
p 4.0e-16
N 239,268
Large GWAS
European

hepcidin:ferritin ratio

Galesloot TE et al. “Meta-GWAS and Meta-Analysis of Exome Array Studies Do Not Reveal Genetic Determinants of Serum Hepcidin.” Plos One 11(11):e0166628 (2016)
Allele T
OR 0.31
p 3.0e-14
N 6,201
Meta-analysis
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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