rs141235885
This variant is located in the DSTYK gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
platelet volume
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.06
p 1.0e-20
N 394,642
Large GWAS
European
▶ClinVar annotation
Benign★☆☆☆
2 submittersnot provided; Thymoma; Sarcoma; Cholangiocarcinoma; Malignant tumor of esophagus
View on ClinVar →About DSTYK
This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
View all DSTYK variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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