rs141313898

This is a protein-altering variant in the SURF2 gene.

GWAS Catalog Trait Associations (8)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

E-selectin amount

Allele G
OR 0.27
p 8.0e-27
N 47,745
Large GWAS
European

alkaline phosphatase measurement

Allele G
OR 0.17
p 3.0e-23
N 394,642
Large GWAS
European
Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.20
p 1.0e-17
N 355,891
Major Consortium StudyLarge GWAS
multi-ancestry

histo-blood group ABO system transferase measurement

Allele G
OR 0.27
p 2.0e-22
N 47,745
Large GWAS
European

intercellular adhesion molecule 2 measurement

Allele G
OR 0.26
p 5.0e-21
N 47,745
Large GWAS
European

intestinal-type alkaline phosphatase measurement

Allele G
OR 0.32
p 4.0e-18
N 47,745
Large GWAS
European

protein FAM3D measurement

Allele G
OR 0.34
p 1.0e-15
N 47,745
Large GWAS
European

intercellular adhesion molecule 5 measurement

Allele G
OR 0.26
p 4.0e-12
N 47,745
Large GWAS
European

About SURF2

This gene shares a bidirectional promoter with surfeit 1 (SURF1; GeneID: 6834), which is located on the opposite strand. It encodes a conserved protein that is expressed in a variety of tissues. [provided by RefSeq, Jul 2013]

View all SURF2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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