rs142071177

This is a intron variant variant in the TMEM145 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cD177 antigen measurement

Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)

Allele T

OR 0.63

p 3.0e-13

N 2,935

Large GWAS

Greater Middle Eastern (Middle Eastern, North African or Persian)

About TMEM145

Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all TMEM145 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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