rs142556838
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Tachycardia
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.22
p 8.0e-30
N 595,515
Major Consortium StudyLarge GWAS
multi-ancestry
heart rate response to exercise
Cai L et al. “Causal associations between cardiorespiratory fitness and type 2 diabetes.” Nature Communications 14(1):3904 (2023)
Allele C
OR 0.62
p 2.0e-24
N 69,416
Large GWAS
European
diastolic blood pressure
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.03
p 2.0e-13
N 485,677
Large GWAS
multi-ancestry
maximal oxygen uptake measurement
Hanscombe KB et al. “The genetic case for cardiorespiratory fitness as a clinical vital sign and the routine prescription of physical activity in healthcare.” Genome Medicine 13(1):180 (2021)
Allele C
OR 0.05
p 3.0e-9
N 70,783
Large GWAS
European
heart rate response to recovery post exercise
Diamant N et al. “Deep learning on resting electrocardiogram to identify impaired heart rate recovery.” Cardiovascular Digital Health Journal 3(4):161-170 (2022)
Allele C
OR 0.31
p 2.0e-8
N 43,722
Major Consortium StudyLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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