rs142614204

This variant is located in the OSTN gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

immune system disease

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele G

OR 3.13

p 1.0e-13

N 630,445

Major Consortium StudyLarge GWAS

multi-ancestry

About OSTN

Predicted to enable signaling receptor binding activity. Involved in negative regulation of dendrite extension. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]

View all OSTN variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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