rs142678293

This variant is located in the RALGAPB gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body mass index

Huang J et al. “Genomics and phenomics of body mass index reveals a complex disease network.” Nature Communications 13(1):7973 (2022)

Allele C

OR 0.04

p 2.0e-8

N 1,122,049

Large GWAS

European

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ClinVar annotation

Benign

1 submitter

RALGAPB-related disorder

View on ClinVar →

About RALGAPB

Enables protein heterodimerization activity. Predicted to be involved in Ral protein signal transduction and activation of GTPase activity. Predicted to act upstream of or within regulation of exocyst localization and regulation of protein localization. [provided by Alliance of Genome Resources, Jul 2025]

View all RALGAPB variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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