rs142718878

This variant is located in the RENBP gene.

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ClinVar annotation

Benign★★★☆

3 submitters2 publications

not provided; Gastric cancer; Ovarian serous cystadenocarcinoma; Lung cancer

About RENBP

The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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