rs142741123
This is a intron variant variant in the MYO1B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
esophageal squamous cell carcinoma
Chen WC et al. “Genome-wide association study of esophageal squamous cell cancer identifies shared and distinct risk variants in African and Chinese populations.” American Journal of Human Genetics 110(10):1690-1703 (2023)
Allele C
OR 2.66
p 5.0e-8
N 4,903
Large GWAS
Sub-Saharan African
About MYO1B
Enables ATP binding activity; actin filament binding activity; and microfilament motor activity. Involved in actin filament organization and post-Golgi vesicle-mediated transport. Located in several cellular components, including actin filament; endosome; and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all MYO1B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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