rs142988850
This variant is located in the GAL3ST4 gene.
▶GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of endosialin in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.45
p 1.0e-34
N 47,745
Large GWAS
European
versican core protein measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.34
p 1.0e-29
N 47,745
Large GWAS
European
level of plexin domain-containing protein 1 in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.44
p 3.0e-28
N 47,745
Large GWAS
European
microfibrillar-associated protein 5 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.30
p 3.0e-16
N 47,745
Large GWAS
European
aggrecan core protein measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.25
p 4.0e-14
N 47,745
Large GWAS
European
level of receptor-type tyrosine-protein phosphatase zeta in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.26
p 6.0e-14
N 47,745
Large GWAS
European
level of soluble scavenger receptor cysteine-rich domain-containing protein SSC5D in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.27
p 7.0e-14
N 47,745
Large GWAS
European
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitter1 publicationAbout GAL3ST4
This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates. [provided by RefSeq, Jul 2008]
View all GAL3ST4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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