rs143291877

This is a stop gained variant in the FNTB gene.

ClinVar annotation

Pathogenic☆☆☆
2 submitters1 publication

Pheochromocytoma

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About FNTB

Enables acetyltransferase activator activity; enzyme binding activity; and zinc ion binding activity. Contributes to protein farnesyltransferase activity. Involved in protein farnesylation and regulation of microtubule-based movement. Part of microtubule associated complex and protein farnesyltransferase complex. Implicated in anxiety disorder. [provided by Alliance of Genome Resources, Jul 2025]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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