rs143378550

▶

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

aspartate aminotransferase measurement

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)

Allele A

OR 0.08

p 2.0e-20

N 928,679

Large GWAS

multi-ancestry

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele A

OR 0.06

p 7.0e-13

N 493,058

Large GWAS

multi-ancestry

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.05

p 9.0e-16

N 394,642

Large GWAS

European

diverticular disease

Wu Y et al. “150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.” Cell Genomics 3(7):100326 (2023)

Allele A

OR 0.15

p 9.0e-18

N 454,768

Large GWAS

European

anterior thigh muscle fat infiltration measurement

van der Meer D et al. “The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition.” Communications Biology 5(1):1271 (2022)

Allele A

OR 6.67

p 3.0e-11

N 32,911

Large GWAS

European

sex hormone-binding globulin measurement

Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)

Allele A

OR 0.02

p 4.0e-8

N 188,908

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

rs143378550

GWAS Catalog Trait Associations (4)

aspartate aminotransferase measurement

diverticular disease

anterior thigh muscle fat infiltration measurement

sex hormone-binding globulin measurement

Community Wiki

Comments