rs143507801
This is a intron variant variant in the MED13L gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
gut microbiome measurement
Qin Y et al. “Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort.” Nature Genetics 54(2):134-142 (2022)
Allele G
OR 0.20
p 6.0e-11
N 5,959
Large GWAS
European
About MED13L
The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010]
View all MED13L variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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