rs143825102
This is a downstream gene variant variant in the OXTR gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Struvite nephrolithiasis
Hsi RS et al. “Evaluation of Genetic Associations with Clinical Phenotypes of Kidney Stone Disease.” European Urology Open Science 67:38-44 (2024)
Allele T
OR 9.32
p 4.0e-8
N 85,435
Large GWAS
European, African unspecified, NR
About OXTR
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
View all OXTR variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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