rs14399

This is a 3 prime utr variant variant in the SLC16A10 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

tyrosine measurement

Kettunen J et al. “Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.” Nature Communications 7:11122 (2016)

Allele A

OR —

β 0.100

p 1.0e-24

N 24,925

Large GWAS

European

alcohol consumption quality

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)

Allele A

OR 0.01

p 4.0e-10

N 2,965,643

Large GWAS

European, East Asian, Hispanic or Latin American, African unspecified

About SLC16A10

SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.[supplied by OMIM, Apr 2004]

View all SLC16A10 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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