rs144409664
This variant is located in the ADM gene.
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitter1 publicationAbout ADM
The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014]
View all ADM variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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