rs1444782

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

eosinophil count

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.04

p 5.0e-75

N 394,642

Large GWAS

European

Vuckovic D et al. “The Polygenic and Monogenic Basis of Blood Traits and Diseases.” Cell 182(5):1214-1231.e11 (2020)

Allele A

OR 0.02

p 1.0e-14

N 408,112

Large GWAS

European

Höglund J et al. “Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count.” Frontiers in Immunology 13:862255 (2022)

Allele A

OR 0.04

p 4.0e-28

N 365,954

Large GWAS

European

asthma

Zhu Z et al. “Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.” The European Respiratory Journal 54(6) (2019)

Allele G

OR 1.10

p 1.0e-48

N 394,283

Large GWAS

multi-ancestry

Olafsdottir TA et al. “Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis.” Nature Communications 11(1):393 (2020)

Allele G

OR 1.10

p 9.0e-48

N 771,388

Large GWAS

European

Valette K et al. “Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank.” Communications Biology 4(1):700 (2021)

Allele G

OR 0.10

p 2.0e-47

N 408,422

Major Consortium StudyLarge GWAS

European

Nasal Cavity Polyp

Kristjansson RP et al. “A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis.” Nature Genetics 51(2):267-276 (2019)

Allele G

OR 1.19

p 1.0e-14

N 719,047

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

rs1444782

GWAS Catalog Trait Associations (3)

eosinophil count

asthma

Nasal Cavity Polyp

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