rs145044782
This is a intron variant variant in the GLCCI1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
response to darapladib, Diarrhea
Yeo A et al. “Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.” Plos One 12(7):e0182115 (2017)
Allele A
OR 10.88
p 3.0e-8
N 212
Meta-analysisSmall GWAS
European
About GLCCI1
This gene encodes a protein of unknown function. Expression of this gene is induced by glucocorticoids and may be an early marker for glucocorticoid-induced apoptosis. Single nucleotide polymorphisms in this gene are associated with a decreased response to inhaled glucocorticoids in asthmatic patients. [provided by RefSeq, Feb 2012]
View all GLCCI1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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