rs145078947

This is a protein-altering variant in the TMEM251 gene.

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GWAS Catalog Trait Associations (36)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

probable serine carboxypeptidase CPVL measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.84
p 6.0e-189
N 47,745
Large GWAS
European

level of ribonuclease T2 in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.93
p 3.0e-116
N 47,745
Large GWAS
European

level of phospholipase A2 group XV in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.99
p 3.0e-93
N 47,745
Large GWAS
European

level of carboxypeptidase Q in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 1.00
p 1.0e-88
N 47,745
Large GWAS
European

lysosomal Pro-X carboxypeptidase measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.82
p 2.0e-68
N 47,745
Large GWAS
European

level of N-sulphoglucosamine sulphohydrolase in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.69
p 5.0e-65
N 47,745
Large GWAS
European

protein CREG1 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.84
p 8.0e-63
N 47,745
Large GWAS
European

cation-independent mannose-6-phosphate receptor measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.82
p 4.0e-58
N 47,745
Large GWAS
European

acid sphingomyelinase-like phosphodiesterase 3a measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.69
p 1.0e-57
N 47,745
Large GWAS
European

dipeptidyl peptidase 1 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.71
p 8.0e-56
N 47,745
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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