rs1460678

This is a intron variant variant in the FIGN gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

BMI-adjusted waist circumference

Christakoudi S et al. “GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.” Scientific Reports 11(1):10688 (2021)

Allele G

OR 0.03

p 2.0e-10

N 219,872

Major Consortium StudyLarge GWAS

European

body mass index

Winkler TW et al. “The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.” Plos Genetics 11(10):e1005378 (2015)

Allele C

OR —

β 0.026

p 4.0e-8

N 309,889

Large GWAS

European

About FIGN

Predicted to enable ATP hydrolysis activity and microtubule severing ATPase activity. Predicted to be involved in cell division and microtubule cytoskeleton organization. Predicted to act upstream of or within locomotory behavior. Predicted to be located in nuclear matrix. [provided by Alliance of Genome Resources, Jul 2025]

View all FIGN variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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