rs146644517

This is a intergenic variant variant.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of MHC class I polypeptide-related sequence A in blood, level of MHC class I polypeptide-related sequence B in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.55

p 3.0e-42

N 47,745

Large GWAS

European

trait in response to traditional medicine, drug-induced liver injury

Nakamura R et al. “Significant association between HLA-B*35:01 and onset of drug-induced liver injury caused by Kampo medicines in Japanese patients.” Hepatology Research : the Official Journal of the Japan Society of Hepatology 53(5):440-449 (2023)

Allele A

OR —

p 9.0e-10

N 3,012

Large GWAS

East Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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