rs146689733
This is a upstream gene variant variant in the MTHFSD gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of methenyltetrahydrofolate synthase domain-containing protein in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.48
p 1.0e-26
N 47,745
Large GWAS
European
About MTHFSD
Enables RNA binding activity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all MTHFSD variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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