rs146760080
This is a protein-altering variant in the DECR2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Hodgkins lymphoma
Osman Y et al. “Functional multigenic variations associated with hodgkin lymphoma.” International Journal of Laboratory Hematology 43(6):1472-1482 (2021)
Allele C
OR —
β 0.040
p 2.0e-12
N 97
Small GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
About DECR2
Enables 2,4-dienoyl-CoA reductase (NADPH) activity and trans-2-enoyl-CoA reductase (NADPH) activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in cytosol and peroxisomal membrane. Predicted to be active in peroxisome. [provided by Alliance of Genome Resources, Jul 2025]
View all DECR2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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